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A therapeutic blood draw for testosterone levels is a procedure that can help manage the risks of high red blood cell levels associated with testosterone replacement therapy (TRT). Doctors often recommend that men on TRT have a therapeutic blood draw every 120 days. Here's some information about therapeutic blood draws for testosterone levels: Procedure -A healthcare professional uses a needle to draw a blood sample from a vein in your arm. The procedure is similar to donating blood and usually takes less than an hour. Risks - There's very little risk to getting a testosterone blood test, but you might experience slight tenderness or bruising at the needle site. Blood donation - Blood banks and mobile blood drives typically don't accept blood from testosterone patients, but some may if they have a special variance. Insurance - Some blood donation centers will bill your insurance company if your insurance covers therapeutic phlebotomy. A testosterone test can help determine if your testosterone levels are normal for your age and identify factors that might affect your health. Testosterone is the main male sex hormone, and it helps with the development of muscles, growth of body and facial hair, and deepening of the voice